Federico Fazio was born in Buenos Aires, Argentina on March 17 1987. Fazio started learning football when he was young. In 2005, he became a professional football player of the Primera B Nacional with Ferro Carril Oeste. For his outstanding performance and unremitting efforts, he was bought by a Spanish club Sevilla FC in 2007. For the absences of two football players, he took an important position in the football team, obtaining the qualification to the UEFA cup. In 2007, he accomplished the first appearance with the main squad in August.
In the next year, the football team finished at the third place but Fazio with slightly less and saw time at both places. Due to severe injuries, he only participated in ten league matches. In August, 2014, Fazio signed a four-year contract with the Tottenham Hotspur for a large sum of transfer fee. In 2016, he was loaned to A.S. Roma with Italians, in which he got the opportunity to become a regular member of the football club for €3.2 million.